Animal
Herpesvirus B Biological Agent Reference Sheet (BARS)
Last revised 03/05/2024
This information has been prepared to align with the NIH B Virus Resource Program guidelines and recommendations.
ABP Human Cells in Rodents
1. Purpose and Scope
This Animal Biosafety Procedure (ABP) describes prudent practices, procedures, and equipment to reduce risk when implanting human cells in rodents at Animal Biosafety Level 2 (ABSL-2). Potential hazards include bloodborne pathogens (BBPs) such as HIV, Hepatitis B, Hepatitis C, and other human bloodborne pathogens. It is important to recognize that BBPs are not limited to HIV and Hepatitis viruses; other pathogens, such as syphilis, malaria, and certain arboviruses, can also pose risks.
ABP Use of Formaldehyde for Fixation of Whole Animals and Tissues
1. Purpose and Scope
This Animal Biosafety Procedure (ABP) outlines the practices and procedures for working with formaldehyde (37% solution) and paraformaldehyde (white crystalline powder of polymerized formaldehyde) in whole animals or tissues, particularly during perfusion fixation, which poses a higher exposure risk than immersion. Formaldehyde is a carcinogen, and its use must comply with OSHA standards:
ABP Carcinogens and Other Toxic Chemicals in Rodents
1. Purpose and Scope
This Animal Biosafety Procedure (ABP) outlines prudent practices, procedures, and equipment to reduce risks when introducing carcinogens and other toxic chemical agents in laboratory rodents. Specific precautions will vary depending on the particular chemical, dose, route of administration, and metabolism of the chemical. An agent is considered carcinogenic or toxic if indicated in the Safety Data Sheet (SDS) or listed in Reference documents (Section 9).
Animal Biosafety Procedures (ABPs)
These Animal Biosafety Procedures (ABPs) describe prudent practices, procedures, and equipment to reduce risk when performing various procedures at Animal Biosafety Level 2 (ABSL-2).
Animal Biosafety
Animal Biosafety and Zoonotic Disease Risk
In-vivo research requires investigators and laboratory personnel to take additional safety precautions to minimize the incidence of disease and allergy.