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9.8 Reproductive Toxins

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A reproductive toxin is a chemical, biological, or physical agent that can adversely affect reproductive function, fertility, pregnancy outcomes, or fetal development. These effects may occur through impacts on reproductive organs, gamete production, hormone regulation, or embryo–fetal development. Reproductive toxins can affect people of all genders.

It is important to understand which hazardous materials are used in laboratory procedures. Many reproductive toxins are chronic health hazards, meaning adverse effects may occur after repeated or prolonged exposure. Individuals who are pregnant or may become pregnant—as well as those planning families—should take extra care when handling known or suspected reproductive toxicants.

EHS provides free and confidential consultation services for individuals with concerns about workplace exposures, engineering controls, work practices, or PPE related to reproductive hazards. Assistance can be requested by completing the Reproductive Health Questionnaire or by visiting the Reproductive Health webpage.

The following precautions should be taken when working with reproductive toxins or other potentially hazardous materials:

  • Wear appropriate personal protective equipment (PPE), including gloves, eye protection, and a lab coat.
  • Select gloves based on compatibility with the specific chemical hazards (consult SDS Section 8).
  • Do not eat, drink, chew gum, or apply cosmetics in areas where hazardous materials are used.
  • Maintain an accurate chemical inventory and ensure containers are clearly labeled.
  • Plan each procedure in advance and ensure appropriate engineering controls and PPE are available.
  • Use the minimum quantity of reproductive toxicant necessary for the procedure.
  • Conduct work involving reproductive toxins in a designated or controlled area as described in the Laboratory Safety Manual for Particularly Hazardous Substances (PHS).
  • Use appropriate engineering controls such as fume hoods, biosafety cabinets, ventilated enclosures, or glove boxes when handling hazardous materials. If these are not feasible, contact EHS regarding respiratory protection requirements.
  • Ensure work surfaces are cleanable and, when necessary, protected with impervious or disposable coverings.
  • Wash hands and forearms thoroughly after completing work and clean all contaminated surfaces and equipment.
  • Do not wear contaminated PPE outside the laboratory or designated work areas.
  • Transport waste containers in a secondary container to prevent contamination during removal from the controlled area.
  • If medical evaluation is needed, provide your healthcare provider with relevant SDSs and procedural information.
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