Appendix J - Peroxide Forming Chemicals
Peroxide Forming Chemicals
Peroxide Guide
| SAFE STORAGE PERIODS FOR PEROXIDE FORMERS | |
| Unopened chemicals from manufacturer | 18 months or (expiration date) |
| Opened containers: | |
| Chemicals in Table A | 3 months |
| Chemicals in Tables B and D | 12 months |
| Uninhibited chemicals in Table C | 24 hours |
| Inhibited chemicals in Table C (Do not store under an inert atmosphere) | 12 months |
| A. Chemicals that form explosive levels of peroxides without concentration | ||
| Butadienea | Isopropyl ether | Sodium amide (sodamide) |
| Chloroprenea | Potassium metal | Tetrafluoroethylenea |
| Divinylacetylene | Potassium amide | Vinylidene chloride |
| B. Chemicals that form explosive levels of peroxides on concentration | ||
| Acetal | Diethyl ether | 4-Methyl-2-pentanol |
| Acetaldehyde | Diethylene glycol dimethyl ether (diglyme) | 2-Pentanol |
| Benzyl alcohol | Dioxanes | 4-Penten-1-ol |
| 2-Butanol | Ethylene glycol dimethyl ether (glyme) | 1-Phenylethanol |
| Cumene | 4-Heptanol | 2-Phenylethanol |
| 2-Cyclohexen-1-ol | 2-Hexanol | 2-Propanol |
| Cyclohexene | Methylacetylene | Tetrahydrofuran |
| Decahydronaphthalene | 3-Methyl-1-butanol | Tetrahydronaphthalene |
| Diacetylene | Methylcyclopentane | Vinyl ethers |
| Dicyclopentadiene | Methyl isobutyl ketone | Other secondary alcohols |
| C. Chemicals that may autopolymerize as a result of peroxide accumulation | ||
| Acrylic acidb | Methyl methacrylateb | Vinyl chloride |
| Acrylonitrileb | Styrene | Vinylpyridine |
| Butadienec | Tetrafluoroethylenec | Vinyladiene chloride |
| Chloroprenec | Vinyl acetate | |
| Chlorotrifluoroethylene | Vinylacetylene | |
D. Chemicals that may form peroxides but cannot clearly be placed in sections A-C | ||
| Acrolein | p-Chlorophenetole | 4,5-Hexadien-2-yn-1-ol |
| Allyl etherd | Cyclooctened | n-Hexyl ether |
| Allyl ethyl ether | Cyclopropyl methyl ether | o,p-Iodophenetole |
| Allyl phenyl ether | Diallyl etherd | Isoamyl benzyl etherd |
| p-(n-Amyloxy)benzoyl chloride | p-Di-n-butoxybenzene | Isoamyl etherd |
| n-Amyl ether | 1,2-Dibenzyloxyethaned | Isobutyl vinyl ether |
| Benzyl n-butyl etherd | p-Dibenzyloxybenzened | Isophoroned |
| Benzyl etherd | 1,2-Dichloroethyl ethyl Ether | B-Isopropoxypropionitriled |
| Benzyl ethyl etherd | 2,4-Dichlorophenetole | Isopropyl 2,4,5-trichloro- phenoxy- acetate |
| Benzyl methyl ether | Diethoxymethaned | Limonene |
| Benzyl 1-napthyl etherd | 2,2-Diethoxypropane | 1,5-p-Methadiene |
| 1,2-Bis(2-chloroethoxy) Ethane | Diethyl ethoxymethylene- Malonate | Methyl p-(n-amyloxy)- benzoate |
| Bis(2 ethoxyethyl)ether | Diethyl fumarated | 4-Methyl-2-pentanone |
| Bis(2-(methoxyethoxy)- ethyl) ether | Diethyl acetald | n-Methylphenetole |
| Bis(2-chloroethyl)ether | Diethyketenef | 2-Methyltetrahydrofuran |
| Bis(2-ethoxyethyl)adipate | m,o,p-diethoxybenzene | 3-Methoxy-1-butyl acetate |
| Bis(2-ethoxyethyl)phthalate | 1,2-Diethoxyethane | 2-Methoxyethanol |
| Bis(2-methoxyethyl)- Carbonate | Dimethoxymethaned | 3-Methoxyethyl acetate |
| Bis(2-methoxyethyl) ether | 1,1-Dimethoxyethaned | 2-Methoxyethyl vinyl ether |
| Bis(2-methoxyethyl) Phthalate | Dimethylketenef | Methonxy-1,3,5,7-cyclo- octa-tetraene |
| Bis(2-methoxymethyl) Adipate | 3,3-Dimethoxypropene | B-Methoxypropionitrile |
| Bis(2-n-butoxyethyl) Phthalate | 2,4-Dinitrophenetole | m-Nitrophenetole |
| Bis(2-phenoxyethyl) ether | 1,3-Dioxepaned | 1-Octene |
| Bis(4-chlorobutyl) ether | Di(1-propynyl)etherf | Oxybis(2-ethyl acetate) |
| Bis(chloromethyl) ethere | Di(2-propynyl)ether | Oxybis(2-ethyl benzoate) |
| 2-Bromomethyl ethyl ether | Di-n-propoxymethaned | B,B-oxydipropionitrile |
| B-Bromophenetole | 1,2-Epoxy-3-isopropoxy- propaned | 1-Pentene |
| o-Bromophenetole | 1,2-Epoxy-3-phenoxy- propane | Phenoxyacetyl chloride |
| p-Bromophenetole | p-Ethoxyacethophenone | a-Phenoxypropionyl chloride |
| 3-Bromopropyl phenyl ether | 2-Ethoxyethyl acetate | Phenyl o-propyl ether |
| 1,3-Butadiyne | (2-Ethoxyethyl)-o-benzoyl benzoate | p-Phenylphenetone |
| Buten-3-yne | 1-(2-Ethoxyethoxy)ethyl acetate | n-Propyl ether |
| tert-Butyl ethyl ether | 1-Ethoxynaphthalene | n-Propyl isopropyl ether |
| tert-Butyl methyl ether | o,p-Ethoxyphenyl isocyanate | Sodium 8,11,14-eicosa- tetraenoate |
| n-Butyl phenyl ether | 1-Ethoxy-2-propyne | Sodium ethoxyacetylidef |
| n-Butyl vinyl ether | 3-Ethoxyopropionitrile | Tetrahydropyran |
| Chloroacetaldehyde diethylacetald | 2-Ethylacrylaldehyde oxime | Triethylene glycol diacetate |
| 2-Chlorobutadiene | 2-Ethylbutanol | Triethylene glycol diprop- ionate |
| 1-(2-Chloroethoxy)-2- phen-oxyethane | Ethyl B-ethoxypropionate | 1,3,3-Trimethoxypropened |
| Chloroethylene | 2-Ethylhexanal | 1,1,2,3-Tetrachloro-1,3- butadiene |
| Chloromethyl methyl ethere | Ethyl vinyl ether | 4-Vinyl cyclohexene |
| B-Chlorophenetole | Furan | Vinylene carbonate |
| o-Chlorophenetole | 2,5-Hexadiyn-1-ol | Vinylidene chlorided |
| NOTES: a When stored as a liquid monomer. b Although these chemicals form peroxides, no explosions involving these monomers have been reported. c When stored in liquid form, these chemicals form explosive levels of peroxides without concentration. They may also be stored as a gas in gas cylinders. When stored as a gas, these chemicals may autopolymerize as a result of peroxide accumulation. d These chemicals easily form peroxides and should probably be considered under Part B. e OSHA - regulated carcinogen. f Extremely reactive and unstable compound. | ||
References: Prudent Practices in the Laboratory, National Research Council, 1995.“Review of Safety Guidelines for Peroxidizable Organic Chemicals,” Chemical Healthand Safety, September/October 1996.