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Appendix J - Peroxide Forming Chemicals

Peroxide Forming Chemicals 

Peroxide Guide

Unopened chemicals from manufacturer 18 months or (expiration date)
Opened containers:
Chemicals in Table A 3 months
Chemicals in Tables B and D 12 months
Uninhibited chemicals in Table C 24 hours
Inhibited chemicals in Table C (Do not store under an inert atmosphere) 12 months
A. Chemicals that form explosive levels of peroxides without concentration
Butadienea Isopropyl ether Sodium amide (sodamide)
Chloroprenea Potassium metal Tetrafluoroethylenea
Divinylacetylene Potassium amide Vinylidene chloride
 B. Chemicals that form explosive levels of peroxides on concentration
Acetal Diethyl ether 4-Methyl-2-pentanol
Acetaldehyde Diethylene glycol dimethyl ether (diglyme) 2-Pentanol
Benzyl alcohol Dioxanes 4-Penten-1-ol
2-Butanol Ethylene glycol dimethyl ether (glyme) 1-Phenylethanol
Cumene 4-Heptanol 2-Phenylethanol
2-Cyclohexen-1-ol 2-Hexanol 2-Propanol
Cyclohexene Methylacetylene Tetrahydrofuran
Decahydronaphthalene 3-Methyl-1-butanol Tetrahydronaphthalene
Diacetylene Methylcyclopentane Vinyl ethers
Dicyclopentadiene Methyl isobutyl ketone Other secondary alcohols
C. Chemicals that may autopolymerize as a result of peroxide accumulation
Acrylic acidb Methyl methacrylateb Vinyl chloride
Acrylonitrileb Styrene Vinylpyridine
Butadienec Tetrafluoroethylenec Vinyladiene chloride
Chloroprenec Vinyl acetate
Chlorotrifluoroethylene Vinylacetylene
D. Chemicals that may form peroxides but cannot clearly be placed in sections A-C
Acrolein p-Chlorophenetole 4,5-Hexadien-2-yn-1-ol
Allyl etherd Cyclooctened n-Hexyl ether
Allyl ethyl ether Cyclopropyl methyl ether o,p-Iodophenetole
Allyl phenyl ether Diallyl etherd Isoamyl benzyl etherd
p-(n-Amyloxy)benzoyl chloride p-Di-n-butoxybenzene Isoamyl etherd
n-Amyl ether 1,2-Dibenzyloxyethaned Isobutyl vinyl ether
Benzyl n-butyl etherd p-Dibenzyloxybenzened Isophoroned
Benzyl etherd 1,2-Dichloroethyl ethyl Ether B-Isopropoxypropionitriled
Benzyl ethyl etherd 2,4-Dichlorophenetole Isopropyl 2,4,5-trichloro- phenoxy- acetate
Benzyl methyl ether Diethoxymethaned Limonene
Benzyl 1-napthyl etherd 2,2-Diethoxypropane 1,5-p-Methadiene
1,2-Bis(2-chloroethoxy) Ethane Diethyl ethoxymethylene- Malonate Methyl p-(n-amyloxy)- benzoate
Bis(2 ethoxyethyl)ether Diethyl fumarated 4-Methyl-2-pentanone
Bis(2-(methoxyethoxy)- ethyl) ether Diethyl acetald n-Methylphenetole
Bis(2-chloroethyl)ether Diethyketenef 2-Methyltetrahydrofuran
Bis(2-ethoxyethyl)adipate m,o,p-diethoxybenzene 3-Methoxy-1-butyl acetate
Bis(2-ethoxyethyl)phthalate 1,2-Diethoxyethane 2-Methoxyethanol
Bis(2-methoxyethyl)- Carbonate Dimethoxymethaned 3-Methoxyethyl acetate
Bis(2-methoxyethyl) ether 1,1-Dimethoxyethaned 2-Methoxyethyl vinyl ether
Bis(2-methoxyethyl) Phthalate Dimethylketenef Methonxy-1,3,5,7-cyclo- octa-tetraene
Bis(2-methoxymethyl) Adipate 3,3-Dimethoxypropene B-Methoxypropionitrile
Bis(2-n-butoxyethyl) Phthalate 2,4-Dinitrophenetole m-Nitrophenetole
Bis(2-phenoxyethyl) ether 1,3-Dioxepaned 1-Octene
Bis(4-chlorobutyl) ether Di(1-propynyl)etherf Oxybis(2-ethyl acetate)
Bis(chloromethyl) ethere Di(2-propynyl)ether Oxybis(2-ethyl benzoate)
2-Bromomethyl ethyl ether Di-n-propoxymethaned B,B-oxydipropionitrile
B-Bromophenetole 1,2-Epoxy-3-isopropoxy- propaned 1-Pentene
o-Bromophenetole 1,2-Epoxy-3-phenoxy- propane Phenoxyacetyl chloride
p-Bromophenetole p-Ethoxyacethophenone a-Phenoxypropionyl chloride
3-Bromopropyl phenyl ether 2-Ethoxyethyl acetate Phenyl o-propyl ether
1,3-Butadiyne (2-Ethoxyethyl)-o-benzoyl benzoate p-Phenylphenetone
Buten-3-yne 1-(2-Ethoxyethoxy)ethyl acetate n-Propyl ether
tert-Butyl ethyl ether 1-Ethoxynaphthalene n-Propyl isopropyl ether
tert-Butyl methyl ether o,p-Ethoxyphenyl isocyanate Sodium 8,11,14-eicosa- tetraenoate  
n-Butyl phenyl ether 1-Ethoxy-2-propyne Sodium ethoxyacetylidef
n-Butyl vinyl ether 3-Ethoxyopropionitrile Tetrahydropyran
Chloroacetaldehyde diethylacetald 2-Ethylacrylaldehyde oxime Triethylene glycol diacetate
2-Chlorobutadiene 2-Ethylbutanol Triethylene glycol diprop- ionate
1-(2-Chloroethoxy)-2- phen-oxyethane Ethyl B-ethoxypropionate 1,3,3-Trimethoxypropened
Chloroethylene 2-Ethylhexanal 1,1,2,3-Tetrachloro-1,3- butadiene
Chloromethyl methyl ethere Ethyl vinyl ether 4-Vinyl cyclohexene
B-Chlorophenetole Furan Vinylene carbonate
o-Chlorophenetole 2,5-Hexadiyn-1-ol Vinylidene chlorided
NOTES: a   When stored as a liquid monomer. b   Although these chemicals form peroxides, no explosions involving these     monomers have been reported. c   When stored in liquid form, these chemicals form explosive levels of peroxides     without concentration. They may also be stored as a gas in gas cylinders.     When stored as a gas, these chemicals may autopolymerize as a result of     peroxide accumulation. d   These chemicals easily form peroxides and should probably be considered      under Part B. e   OSHA - regulated carcinogen. f    Extremely reactive and unstable compound.

References: Prudent Practices in the Laboratory, National Research Council, 1995.“Review of Safety Guidelines for Peroxidizable Organic Chemicals,” Chemical Healthand Safety, September/October 1996.