Mumps Virus Biological Agent Reference Sheet (BARS)

Summary

Agent Characteristics 

Risk Group: RG-2 associated with human disease, rarely serious; preventive or therapeutic interventions often available.

Agent Type: Virus 

Description: Mumps Virus (MuV) is a paramyxovirus that may result in a contagious disease known as Mumps, a well-known childhood disease. The virus is a spherical, enveloped virus with a linear, single-stranded negativesense RNA genome. Most individuals recover from mumps in a few weeks; some individuals may experience mild or no symptoms and may never know they had the disease. 

Host Range: Humans; non-human primates

Host Shedding: Blood, Direct Contact, Saliva, Urine, Airborne spread by breathing, coughing, sneezing                            

Route of Exposure to Humans: Aerosol/Inhalation, Direct Contact, Mucous Membranes, Contaminated Items, Percutaneous, Broken Skin

Infectious Dose: Unknown                           Incubation Period: 15-24 days; median of 19 days

Health Hazards

Signs and symptoms of infection may include:

• Flu-like symptoms (i.e. fever, headache, dehydration, weight loss, lethargy)
• Respiratory symptoms (i.e. coughing, sneezing)
• Neurological symptoms (i.e. loss of sensation, ataxia)
• Aseptic meningitis, deafness, orchitis and swollen salivary glands (parotitis)

Immunizations: Available                               Prophylaxis*: Available

*Formal medical advice is obtained during medical consultations with Cornell Health or primary healthcare provider as needed.

Agent Viability 

For more guidance on disinfection see:  disinfectant selection.

Laboratory Hazards 

• High energy-creating activities (centrifugation, sonication, high pressure systems, vortexing, tube cap popping)
• Handling of sharps (needles, scalpels, microtome blades, broken glass, etc.)
• Splash/droplet-creating activities (shaking incubators, liquid culturing, mechanical pipetting)
• Equipment contamination
• Exposed skin/uncovered wounds

Laboratory Acquired Infection (LAI) History:  8 known cases prior to 1976 – information regarding exposure route or cause not available.

Laboratory Handling Guidelines 

Laboratory Biosafety Level (BSL): BSL-2 with special practices

Attenuated Stain Alternatives: Mumps Virus Enders strain and Jeryl Lynn strain

Waste Management: Regulated Medical Waste (RMW)

Shipping Guidance: Refer to EHS Biological Materials Shipping 

Animal Vivarium Guidance

Animal Housing Biosafety Level (ABSL): ABSL-2

Animal Biosecurity: Experimental animals are housed separately       

Perform Inoculations: In a Biosafety Cabinet

Change Cages: In a Biosafety Cabinet

Exposure and Spill Procedures 

Mucous Membranes: Flush eyes, mouth, or nose for 15 minutes at an eyewash station. See: responding to exposures.

Other Exposures: Wash with soap and water for 15 minutes (open wounds, sores, etc.) or a minimum of 20 seconds for areas with intact skin. See: responding to exposures.

Small Spills: Notify others working in the lab. Evacuate area and allow 30 minutes for aerosols to settle. Don appropriate PPE. Cover area of the spill with paper towels and apply disinfectant, working from the perimeter toward the center. Allow 30 minutes of contact time before disposal and cleanup of spill materials. See: spill cleanup

Large Spills: Request assistance from the EHS Spill Team by calling CUPD dispatch. Call 911 from a campus phone or 607-255-1111 from a mobile phone.

Incident Reporting: Immediately report the incident to supervisor and complete the EHS online injury/illness report as soon as possible.

Medical Follow-Up:

• For students, seek medical attention at Cornell Health or local primary care provider. Call Cornell Health at 607-255-5155 (24-hour phone consultation line) or a local urgent care. 
• For faculty and staff, seek medical evaluation with a local primary care provider or urgent care. Cornell Health does not see employees for post-exposure care. 
• Emergencies: Call 911 from a campus phone or 607-255-1111 from a mobile phone.