7.7 Toxicity
Toxicity refers to the ability of a chemical to cause harmful effects to the body. As was described by Paracelsus (1493-1541):
“What is it that is not poison? All things are poison and nothing is without poison. It is the dose only that makes a thing not a poison.”
There are a number of factors that influence the toxic effects of chemicals on the body. These include, but are not limited to:
- The quantity and concentration of the chemical.
- The length of time and the frequency of the exposure.
- The route of the exposure.
- If mixtures of chemicals are involved.